##  [Cardiovascular, Renal and Metabolic Disease](/us-en/about/therapeutic-areas/cardiovascular-renal "Cardiovascular, Renal and Metabolic Disease") 

 We are redefining how the world tackles cardiovascular, renal and metabolic (CRM) conditions because interconnected diseases require interconnected thinking.  
 At Novartis, we are continuing our 40-year legacy in both cardiovascular (CV) and renal care with our bold science, robust portfolio, and commitment to research and development.

 

In cardiovascular care, we envision a world with no preventable CV deaths and are using cutting-edge science and technology in our mission to ensure no heart is lost too soon.

In kidney disease, we are building on our groundbreaking work that began in transplant, with an expanding portfolio of medicines that address the underlying causes of disease, starting with kidney conditions that have significant unmet need.



 



##  Transforming Outcomes, Rewriting Futures 

Together, we are breaking boundaries – to transform outcomes, improve lives, and build a better world for people with cardiovascular, renal and metabolic diseases.

 [ 

 ![Actor portrayal ](/us-en/sites/novartis_us/files/styles/cards_50_50/public/2026-01/Doctor%20using%20stethoscope%20on%20patient%202%20%28370x220%29_0_0.png.webp?itok=3-p6bbJM "Doctor using stethoscope on patient") 

 

###  Cardiovascular Disease 

Our mission is to ensure no heart is lost too soon. We envision a world where preventable cardiovascular disease related deaths are no longer part of our lives.

 

 

 ](https://www.novartis.com/us-en/cardiovascular-disease) [ 

 ![doctor meeting with a patient](/us-en/sites/novartis_us/files/styles/cards_50_50/public/2026-03/Untitled%20design%20%2842%29.png.webp?itok=6YURycpQ "doctor meeting with a patient") 

 

###  Kidney Disease 

Our mission is to empower breakthroughs and transform care in kidney health, starting with kidney conditions that have significant unmet need.

 

 

 ](https://www.novartis.com/us-en/kidney-disease) 





 

 

 



## Our Pipeline

[Learn more](https://www.novartis.com/research-development/novartis-pipeline?search_api_fulltext=&field_therapeutic_area%5B%5D=2936)



 

 





##  Additional Resources 

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###  Products 



 

 

 ](/us-en/node/33006) [ 

 

###  Clinical Trials 



 

 

 ](https://www.novartis.com/clinicaltrials/study) [ 

 

###  Investigator Initiated Trials 



 

 

 ](https://www.novartis.com/healthcare-professionals/investigator-initiated-trials-studies-clinical-and-investigator-initiated-research-non-clinical) 





 

 

 



##  Other Therapeutic Areas 

 [ 

 ![Two women smiling as they walk together through a sunny park, enjoying a friendly moment.  ](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-10/two-women-smiling-as-they-walk_1.JPG.webp?itok=DY3f7H1A "Two women smiling as they walk together through a sunny park, enjoying a friendly moment.  ") 

 

###  Immunology 

See how we are creating a world where health care professionals have more options and people living with immunological conditions can live their daily lives without limitations.

 

 

 ](https://www.novartis.com/us-en/about/therapeutic-areas/immunology) [ 

 ![smiling patient and two healthcare professionals](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-10/two-smiling-healthcare-professionals-in-a-medical-office-smiling-with-a-patient-as-they-check-his-pulse.png.jpeg.webp?itok=39Yf3l9h "smiling patient and two healthcare professionals") 

 

###  Oncology 

Combining the power of science and empathy to unravel the inner workings of cancer and develop innovative therapies that restore hope to those with cancer and their loved ones. 

 

 

 ](https://www.novartis.com/us-en/about/therapeutic-areas/oncology) [ 

 ![nurse and patient exchanging warm moment](/us-en/sites/novartis_us/files/styles/cards_1_3/public/2025-10/nurse-patient-exchanging-warm-moment.jpg.jpeg.webp?itok=o8iXY9_J "nurse and patient exchanging warm moment") 

 

###  Neuroscience 

Creating a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression. 

 

 

 ](https://www.novartis.com/about/therapeutic-areas/neuroscience)