ESMO 2021: Novartis-Medikament zeigt das längste bisher berichtete mediane Gesamtüberleben bei Frauen mit fortgeschrittenem HR+/HER2- Mammakarzinom
Login für Journalisten
Der geschützte Novartis-Pressebereich beinhaltet Pressemitteilungen der deutschen Novartis-Gesellschaft und des Konzerns sowie entsprechendes Bildmaterial. Als geschlossener Benutzerkreis ist er vollumfänglich nur Journalisten zugänglich.
Referenzen
- Hortobagyi GN et al. Overall survival (OS) results from the phase III MONALEESA (ML)-2 trial of postmenopausal patients with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2−) advanced breast cancer (ABC) treated with endocrine therapy (ET) ± ribociclib. Presented at the European Society of Medical Oncology (ESMO) Congress, September 16-21, 2021, (Abstract #LBA17).
- Im SA et al. Overall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer. N Engl J Med 2019; 381:307-316.
- Slamon DJ et al. Overall survival with ribociclib plus fulvestrant in advanced breast cancer. N Engl J Med 2020; 382(6):514-524.
- Hortobagyi GN et al. Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer. Ann Oncol 2018; 29:1541-1547.
- Slamon DJ et al. Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: MONALEESA-3. J Clin Oncol 2018; 36:2465-2472.
- Tripathy D et al. Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial. Lancet Oncol 2018; 19:904-915.
- Hortobagyi G et al. Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer. N Engl J Med 2016; 375:1738-1748.
- Gheorghe D. Breast Cancer. Decision Resources 2017; 1-338.
- Fachinformation Kisqali® 200 mg Filmtabletten.
- Kisqali (ribociclib) Prescribing information. East Hanover, New Jersey, USA: Novartis Pharmaceuticals Corporation; July 2018.