Summary
About the Role
Key Responsibilities:
Design, develop, and troubleshoot biochemical/biophysical assays using various detection technologies to identify and characterize cancer targets and small molecule modulators
Measure binding affinity, binding kinetics, and understand the mode of binding of ligands to proteins of interest
Assess and implement emerging cutting edge technologies and novel assay approaches to advance drug discovery programs
Contribute to medicinal chemistry drug discovery efforts to evaluate compound SAR and mode of action characterization
Communicate, collaborate and challenge assumptions to push scientific boundaries with a diverse team of cross-functional scientists
The pay range for this position at commencement of employment is expected to be between $66,000 and $99,000 / year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Essential Requirements:
This position will be located at the Cambridge, MA site and will not have the ability to be located remotely. This position will not require travel as defined by the business (domestic and/ or international).
Minimum of a bachelor’s degree in Biochemistry, Biophysics, Enzymology or a related field with 1+ years of experience with relevant laboratory research experience through employment, internships or co-operative study programs Or minimum of a master’s degree with 0-1 years of experience with relevant laboratory research experience through employment, internships or co-operative study programs
Solid understanding of protein function and enzyme mechanism; experience with biochemical and/or biophysical assay development for protein target and small molecule inhibitor characterizations as well as protein-ligand binding interactions
Strong technical ability at the bench, an eagerness to learn new things, and the willingness to tackle challenging scientific questions
Experience collaborating with multidisciplinary project teams
Experience with one of more of the following: fluorescence-based assay techniques (e.g. HTRF, FP, or quench assays) and label-free technologies (e.g. SPR, ITC, DSF, or mass spectrometry)
Proven ability to analyze, interpret and present data in a clear and concise manner
Excellent team-player, with strong communication and inter-personal skills
Desirable Requirements:
Hands-on experience with automation to enable medium to high throughput assays
Benefits and rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards
Commitment to Diversity and Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
