Active Clinical Trials
Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.
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Study title
Condition
Phase
Location
NCT ID
Study title
Condition
Phase
Location
NCT ID
Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Following YTB323 Administration in Participants With Non-active Progressive Multiple Sclerosis (PMS)
Progressive Multiple Sclerosis
Phase1, Phase2
Australia Canada FranceGermany Italy Spain Switzerland
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NCT06675864
Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
Phase1, Phase2
France Japan United KingdomUnited States
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NCT06704269
Kesimpta (Ofatumumab) in Greek Multiple Sclerosis Patients - an Observational Study
Relapsing Multiple Sclerosis (RMS)
Greece
NCT06486779
Entresto Tablets and Granules for Pediatric Specified Drug-use Survey (Pediatric Chronic Heart Failure)
Pediatric Chronic Heart Failure
Japan
NCT06659393
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Familial Hypercholesterolemia - Heterozygous
Phase3
Argentina Austria BelgiumBrazil China Czechia France Germany Greece Hong Kong Hungary Israel Italy Malaysia Netherlands Poland Portugal South Africa Spain Taiwan Turkey (Türkiye) United Kingdom United States
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NCT06597019
An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB323 in Relapsing Multiple Sclerosis
Relapsing Multiple Sclerosis
Phase1, Phase2
Australia France GermanyItaly Spain Switzerland
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NCT06617793
ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS
Relapsing Remitting Multiple Sclerosis (RRMS)
Phase4
Canada
NCT06733922
A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study
Metastatic Castration-Resistant Prostate Cancer
Phase1
Germany Netherlands SpainSwitzerland United Kingdom United States
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NCT06531499
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Healthy Volunteers, Pulmonary Arterial Hypertension
Phase1, Phase2
Argentina Australia BelgiumBrazil Czechia France Germany Greece Italy Latvia Mexico Poland Portugal Romania Serbia Spain United Kingdom United States
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NCT06649110
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Sickle Cell Disease
Phase3
Brazil Colombia KenyaUganda United States
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NCT06439082
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