Affecting 40 million people worldwide, CSU is an immune-related condition characterized by itchy hives and/or deep tissue swelling (angioedema), which can occur on the face, throat, hands and feet. There is no one measurable indicator of CSU and it may be mistaken for an allergic reaction, making it difficult to diagnose and manage. CSU causes significant emotional distress to people with the disease, with many suffering from sleep deprivation and high rates of anxiety or depression. This shouldn’t have to be their reality. Leveraging expertise in this disease is critical to address the unmet needs of people with CSU to ensure that they receive the care they urgently need.
People with HS experience boil-like abscesses on their skin, often in the most intimate parts of the body, that can burst and result in irreversible scarring. The devastating impact of HS ranges from pain that makes it hard to dress or sit down to psychological challenges that, in many cases, lead to social withdrawal and depression.
Bringing this critical human perspective into scientific understanding is essential to ensure patients receive the care they deserve.
For many people, living with the thick, red, scaly patches of skin caused by PsO means a daily struggle with pain, discomfort and even depression. Understanding day-to-day life with this disease, which affects approximately 159 million people, is vital to better develop and accelerate new therapies.
People with PsA can have multiple manifestations of the disease causing different but equally problematic symptoms. Pain, stiffness and swelling can cause irreversible joint damage and people with PsA can sometimes experience skin plaques, which are raised patches of red skin that are thick, scaly, and itchy. There’s a need to help people with PsA restore a sense of control and possibility in the face of their disease.
Waking up in the night because of back pain and being stiff and tired in the morning is a normal experience for people living with axSpA, a form of inflammatory arthritis that affects the spine and other joints. But that doesn’t have to be the case. By working together, we can help alleviate the burden of diseases like axSpA by turning scientific breakthroughs into medicines that change lives.
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Giving voice to people with a misunderstood disease
Shanelle Gabriel was diagnosed with lupus — a chronic autoimmune disease that mostly affects women of African American and Hispanic descent — while she was at college. Today, as a singer, poet and advocate, she uses her voice to highlight challenges faced by people living with this complex and often misunderstood condition.
Understanding hidradenitis suppurativa through Jasmine’s eyes
Can you imagine being diagnosed with a disfiguring skin disease and being told that there is no cure, and it will be with you for life? A disease that causes such unbearable pain that you struggle to put your clothes on, find it painful to sit down and in some cases are unable to take care of loved ones, participate in hobbies or go to work. This is the case with hidradenitis suppurativa (HS), and also known as acne inversa or Verneuil’s disease.
Resource links
Events and scientific meetings
| AAD | American Academy of Dermatology | https://www.aad.org/ |
| EADV | European Academy of Dermatology and Venereology | https://eadv.org/ |
| WCD | World Congress of Dermatology | https://www.wcd2023singapore.org/ |
| ACR | American college of Rheumatology Convergence | https://rheumatology.org/annual-meeting |
| EULAR | European Alliance of Associations for Rheumatology | https://www.eular.org/ |
| EACCI | European Academy of Allergy & Clinical Immunology | https://eaaci.org/ |
| ACAAI | American College of Allergy, Asthma, and Immunology | https://acaai.org/ |
| Sjögren's Europe | https://www.eu-patient.eu/Members/The-EPF-Members/Associate-Member/sjog… | |
| AAAAI | American Academy of Allergy Asthma & Immunology | https://www.aaaai.org/ |
Other therapeutic areas
Cardiovascular, renal and metabolic
Transforming how the world tackles cardiovascular disease and delivering new treatments for people with chronic kidney diseases
Neuroscience
Creating a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.
Oncology
Combining the power of science and empathy to unravel the inner workings of cancer and develop innovative therapies that restore hope to those with cancer and their loved ones.