Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer

 		Advanced HR+/HER2- Breast Cancer Phase1 Japan
Singapore
United States 		NCT07604571

A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy

 		Extensive-stage Small Cell Lung Cancer (ES-SCLC) Phase1, Phase2 Singapore
United States 		NCT07564401

A Study on the Use of Canakinumab Among Familial Mediterranean Fever and Still's Disease Patients

 		Familial Mediterranean Fever, Still Disease, Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still Disease Switzerland NCT07517250

A Study on the Tolerability, Safety and Effectiveness of Asciminib in Patients With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in the Chronic Phase in Germany

 		Leukemia, Chronic Myeloid Germany NCT07549516

Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment

 		Advanced Malignancies and Hepatic Impairment Phase1 France
Italy
Spain
United Kingdom
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 NCT07422610

A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer

 		Metastatic Castration-resistant Prostate Cancer (mCRPC) Phase1 Australia
Japan
United States 		NCT07570979

Remibrutinib Open Label Roll-over Post-trial Access Protocol

 		Indication of the Parent Protocol Phase3 Bulgaria
Canada
Czechia
France
Poland
South Korea
Spain
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 NCT07456891

A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy

 		Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS) Phase3 Australia
France
Germany
Italy
Japan
Netherlands
Spain
United States
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 NCT07498426

A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)

 		Primary Immune Thrombocytopenia (ITP), Primary Evans Syndrome (ES) Phase2 United States NCT07421167

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

 		Heterozygous or Homozygous Familial Hypercholesterolemia Phase3 Taiwan NCT05682378