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  • Novartis presents promising interim Phase II data of potential first-in-class oral therapy iptacopan (LNP023) in rare renal disease C3 glomerulopathy (C3G)
    Basel, October 26, 2020 — Novartis today announced positive Phase II interim analysis results for iptacopan (LNP023), an investigational oral treatment for C3 glomerulopathy (C3G), presented at the virtually held American Society of Nephrology (ASN) 2020 Annual Meeting.
    Reimagine MedicineNew Scientific DiscoveriesMedical Innovations
  • Novartis acquires Vedere Bio, adding novel optogenetic gene therapy technology for treating blindness
    Basel, October 29, 2020 — Novartis announced today that it has acquired Vedere Bio, adding a powerful new platform for AAV-based delivery of gene therapies and a best-in-class optogenetics program to help reimagine the treatment and prevention of vision loss and blindness. The acquisition builds on the company’s commitment in cell and gene therapy…
    Reimagine MedicineNew Scientific DiscoveriesEye Disorders
  • From Our Labs
    Stopping free radicals at their source

    Compounds that block the production of damaging molecules might shed light on their role in disease—and lead to new therapies.

    Biomedical ResearchNovartis Institutes for BioMedical ResearchNew Scientific DiscoveriesScientific ResearchBiomedical Science
  • From Our Labs
    Reimagining protein sequencing

    Three years after discussing how to reuse an old scientific measuring device, Novartis scientists are now testing this idea as part of an innovative research project.

    Novartis Institutes for BioMedical ResearchReimagine MedicineNew Scientific DiscoveriesNext Generation SequencingScientific Research
  • From Our Labs
    Molecular glue kills cancer cells in mice

    Compounds block a protein involved in many cancers by cementing it shut.

    Biomedical ResearchDrug DiscoveryNovartis Institutes for BioMedical ResearchReimagine MedicineNew Scientific Discoveries
  • From Our Labs
    Minion challenges assumptions about the genome

    A diminutive protein prompts a closer look at DNA dark matter.

    Novartis Institutes for BioMedical ResearchNew Scientific DiscoveriesScientific Discoveries
  • From Our Labs
    How Zika infects the growing brain

    The fast-spreading virus can take multiple routes into developing human nerve cells.

    Biomedical ResearchNovartis Institutes for BioMedical ResearchPostdoc ProgramNew Scientific Discoveries
  • From Our Labs
    How to address the culture gap between academia and industry in biomedicine

    Experts call for significant changes to facilitate the discovery of new treatments.

    Drug DiscoveryNovartis Institutes for BioMedical ResearchNew Scientific DiscoveriesClinical ResearchBiomedical Science
  • From Our Labs
    Hooked on science, Jay Bradner becomes top researcher at Novartis

    New NIBR President Jay Bradner shares on drug discovery, his leadership style and what’s next for his career in biomedical research.

    Biomedical ResearchDrug DiscoveryNovartis Institutes for BioMedical ResearchReimagine MedicineNew Scientific DiscoveriesScientific Research
  • From Our Labs
    Fixing what’s lost in translation
    Drug DiscoveryNovartis Institutes for BioMedical ResearchRare DiseasesNew Scientific DiscoveriesGenetic Disease
  • From Our Labs
    Eye disease tracked to a glitch in starburst cells

    A cellular computing error wreaks havoc on vision.

    Novartis Institutes for BioMedical ResearchNew Scientific DiscoveriesScientific ResearchGenetic Disease
  • From Our Labs
    Countering the genome reprogramming of cancer cells

    Novel PRC2 inhibitor changes the expression of hundreds of genes in lab model

    Biomedical ResearchNovartis Institutes for BioMedical ResearchReimagine MedicineNew Scientific DiscoveriesDrug Design

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