Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV Steroid-refractory Acute Graft vs. Host Disease

 		Steroid-refractory Acute Graft Versus Host Disease Phase4

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

 		Hypercholesterolemia Phase4

Patient's Perspective on the Evolution of Hidradenitis Suppurativa Burden After Secukinumab Initiation

 		Hidradenitis Suppurativa

Evaluating the Safety of Myfortic (Mycophenolate Sodium) in Patients With Lupus Nephritis

 		Lupus Nephritis Taiwan

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

 		Atypical Hemolytic Uremic Syndrome Phase3 Brazil

Study of Safety and of the Mechanism of BLZ945 in ALS Patients

 		Amyotrophic Lateral Sclerosis Phase2 Australia

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

 		Atypical Hemolytic Uremic Syndrome Phase3 Turkey
Japan

Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Intravenous Secukinumab in Patients With GCA or PMR

 		Giant Cell Arteritis, Polymyalgia Rheumatica Phase1 United States
Switzerland
Portugal
Spain
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Long-term Follow-up (LTFU) of Patients Treated With Genome-edited Autologous Hematopoietic Stem and Progenitor Cells (HSPC)

 		Sickle Cell Disease United States

A Study of Safety and Efficacy of KFA115 Alone and in Combination With Pembrolizumab in Patients With Select Advanced Cancers

 		Carcinoma, Non-Small-Cell Lung, Cutaneous Melanoma, Carcinoma, Renal Cell, Carcinoma, Ovarian Epithelial, Nasopharyngeal Carcinoma, Carcinoma, Thymic, Anal Cancer, Mesothelioma, Esophagogastric Cancer, High Microsatellite Instability Colorectal Carcinoma, Squamous Cell Carcinoma of Head and Neck, Triple Negative Breast Neoplasms Phase1 United States
Spain
Japan
Germany
Italy
Hong Kong
Singapore
Taiwan
Canada
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