Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 Glomerulopathy

 		Paroxysmal Nocturnal Hemoglobinuria, C3 Glomerulopathy South Korea NCT07416162

A Real-world Chronic Myelogenous Leukemia (CML) Patient Disease Registry to Describe Patient Experience and Clinical Outcomes Among Patients With CML Receiving Approved First or Second Line Tyrosine Kinase Inhibitor (TKI) Therapy

 		Chronic Myelogenous Leukemia - Chronic Phase United States NCT07091019

Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors

 		Breast Cancer, Non-small Cell Lung Cancer (NSCLC), Gastric/Gastroesophageal Junction (GEJ) Cancer, Bladder Cancer Phase1 Australia
Canada
Japan 		NCT07660055

CINC424A2X01B Rollover Protocol

 		Primary Myelofibrosis, Polycythemia Vera, Graft Versus Host Disease, Acute Myeloid Leukemia, Thalassemia Phase4 South Korea NCT02386800

A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia

 		Hypercholesterolaemia Phase2 United States NCT07610278

A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies

 		Advanced Malignancies Phase1 Italy
Spain 		NCT07340190

Phase I Study of JFI447 [68Ga]Ga-DFC413 and Comparison to FFG233 [68Ga]Ga-NNS309 in Patients With Solid Tumors

 		Metastatic Pancreatic Ductal Adenocarcinoma (PDAC), Non-small Cell Lung Cancer (NSCLC), HR+/HER2- Ductal Breast Cancer (BC), HR+/HER2- Lobular Breast Cancer (BC), Triple Negative Breast Cancer (TNBC), Colorectal Cancer (CRC), Soft Tissue Sarcoma (STS) Phase1 Japan NCT07630961

Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments

 		Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung Cancer, Advanced Solid Tumors Harboring the KRAS G12C Mutation Phase1, Phase2 South Korea NCT07468071

A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers

 		Breast Neoplasms, Carcinoma, Non-Small-Cell Lung Phase1 Netherlands NCT07117214

A Study of Ruxolitinib in Patients With Graft-Versus Host Disease

 		Graft-Versus-Host Disease Japan NCT07594587