Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

 		Secondary Progressive Multiple Sclerosis (SPMS) Phase3 Australia
Canada
Israel
United States
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 NCT07225504

Non-interventional Study to Assess the Effectiveness and Safety of Ribociclib in the Adjuvant Therapy of Hormone Receptor Positive (HR+) HER2-negative Stage II and III Breast Cancer in Real Clinical Practice in Russia

 		Breast Cancer Russia NCT06930859

A Study of DII235 in Adults With Elevated Lipoprotein(a)

 		Lipoprotein Disorder Phase2 Japan
United States 		NCT07235046

Observational Study on Lutetium (177Lu) Vipivotide Tetraxetan to Treat Metastatic Castration Resistant Prostate Cancer

 		Metastatic Castration Resistant Prostate Cancer Italy NCT07093801

Evaluation of 1-Year Clinical Outcomes With Early Inclisiran Initiation in Post-MI Patients

 		Myocardial Infarction Russia NCT07142265

Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients

 		Paroxysmal Nocturnal Hemoglobinuria (PNH) Phase3 Brazil
Colombia
Germany
Italy
Netherlands
United States
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 NCT06934967

Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN

 		Primary Immunoglobulin A Nephropathy (IgAN) Phase3 China
Israel
Japan
United States
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 NCT06994845

Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes

 		Acute Coronary Syndrome Phase3 Japan NCT07102628

Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors

 		Pancreatic Ductal Adenocarcinoma, Non-Small Cell Lung Cancer, HR+/HER2- Ductal and Lobular Breast Cancer, Triple Negative Breast Cancer, Colorectal Cancer, Soft Tissue Sarcoma Phase1 Israel NCT07261631

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease

 		Chronic Kidney Disease Phase1 United States NCT07235059