Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

Multiple Sclerosis Germany

Study Assessing the Efficacy, Safety and PK of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum

PIK3CA-related Overgrowth Spectrum (PROS) Phase2 Canada
France
Germany
Italy
Netherlands
Spain
Switzerland
United Kingdom
United States
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Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

Systemic Lupus Erythematosus Phase3 Brazil
Bulgaria
Canada
China
Czechia
Guatemala
Hungary
Israel
Japan
Poland
Portugal
Singapore
Slovakia
South Africa
Spain
Thailand
Turkey
United States
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Roll-over Study to Allow Continued Access to Ribociclib

Metastatic Breast Cancer Phase4 Argentina
Brazil
Costa Rica
Peru
United States
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Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment

Advanced Breast Cancer Phase4 India

A 24-week Prospective, Open-label, Multicenter, Single-arm rPMS Study in Real-world Setting for Atectura®

Asthma Korea, Republic of

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

FLT3-mutated Acute Myeloid Leukemia Phase2 Austria
Czechia
Germany
Italy
Jordan
Korea, Republic of
Poland
Slovenia
Turkey
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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Oligometastatic Prostate Cancer (OMPC) Phase3 Australia
Austria
Belgium
Canada
Czechia
France
Hungary
Israel
Italy
Japan
Singapore
Slovakia
Spain
Switzerland
Taiwan
United States
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First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of EDI048 in Healthy Volunteers

Healthy Volunteers Phase1 United Kingdom

Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

Systemic Lupus Erythematosus Phase3 Argentina
Australia
Chile
Colombia
France
Germany
India
Italy
Korea, Republic of
Malaysia
Mexico
Romania
Taiwan
United Kingdom
United States
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