Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

 		Achilles Tendinopathy Phase2 France
Germany
United Kingdom
United States
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 NCT05592990

A Masked, Placebo-controlled Study to Assess Iptacopan in Age-related Macular Degeneration

 		Age-Related Macular Degeneration Phase2 United Kingdom NCT05230537

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

 		Atypical Hemolytic Uremic Syndrome Phase3 China
Japan
Spain
Turkey
United Kingdom
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 NCT05935215

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

 		Neuroblastoma Phase1, Phase2 Australia
France
Germany
Singapore
Spain
United Kingdom
United States
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 NCT05429502

Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

 		Lymphatic Malformations Phase2, Phase3 Australia
Belgium
France
Germany
Italy
Spain
United States
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 NCT05948943

A Study to Investigate Efficacy, Safety, and Tolerability of Remibrutinib Compared With Placebo in Adults With CINDU Inadequately Controlled by H1-antihistamines

 		Chronic Inducible Urticaria Phase3 Argentina
Australia
Brazil
Canada
Colombia
France
Germany
Hong Kong
Hungary
India
Israel
Italy
Japan
Korea, Republic of
Malaysia
Netherlands
Poland
Portugal
Romania
Singapore
Slovakia
Spain
Thailand
Turkey
United Kingdom
United States
Vietnam
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 NCT05976243

A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting

 		Hypercholesterolemia Germany NCT05362903

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

 		Myeloid Leukemia, Philadelphia Positive Phase1, Phase2 China
France
Germany
Greece
Hungary
Italy
Japan
Korea, Republic of
Netherlands
Poland
Russian Federation
Thailand
Turkey
United States
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 NCT04925479

Ofatumumab in Portuguese Multiple Sclerosis Patients - an Observational Study

 		Relapsing Multiple Sclerosis Portugal NCT05809986

A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

 		Renal Angiomyolipoma Phase4 Taiwan NCT05252585