Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

 		Advanced Solid Tumor, Diffuse Large B Cell Lymphoma, Lymphoma, T-Cell, Mesothelioma, Malignant, Prostatic Neoplasms, Castration-Resistant, Endometrial Cancer, Ovarian Clear Cell Carcinoma, Metastatic Castration-resistant Prostate Cancer Phase1, Phase2 France
Italy
Korea, Republic of
Poland
Spain
United Kingdom
United States
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 NCT04104776

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

 		Early Breast Cancer Phase3 Australia
Israel
Korea, Republic of
United States
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 NCT05827081

Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-postitive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor.

 		Breast Cancer Phase3 Denmark
Ireland
Spain 		NCT05038735

DFT383 in Pediatric Participants With Nephropathic Cystinosis

 		Nephropathic Cystinosis Phase1, Phase2 United States NCT06910813

A Mobile App-Based Study to Evaluate Disease Burden and Treatment Patterns in Immunoglobulin A Nephropathy (IgAN) in the US

 		Immunoglobulin A Nephropathy United States NCT06952426

Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea.

 		Ankylosing Spondylitis Korea, Republic of NCT06905288

Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants

 		Alzheimer Disease, Mild Cognitive Impairment Phase1 France
Spain 		NCT05469360

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation

 		Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase Phase4 India NCT06427811

Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

 		Juvenile Psoriatic Arthritis Phase1 United States NCT06751238

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

 		ANCA Associated Vasculitis (AAV) Phase2 Israel
Japan
Singapore
United States
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 NCT06868290