Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

A Long-term Safety Study in Brazilian Patients With a Diagnosis of Spinal Muscular Atrophy Treated With Zolgensma

 		Spinal Muscular Atrophies Brazil NCT06019637

Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.

 		Chronic Spontaneous Urticaria Phase3 Argentina
Australia
Brazil
Bulgaria
Canada
Czechia
France
Germany
Hungary
India
Italy
Korea, Republic of
Malaysia
Mexico
Netherlands
Poland
Slovakia
Spain
Switzerland
Taiwan
Thailand
Turkey
United Kingdom
Vietnam
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 NCT06042478

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies

 		Heterozygous or Homozygous Familial Hypercholesterolemia Phase3 Brazil
France
Greece
Israel
Italy
Lebanon
Netherlands
Norway
Poland
Slovenia
South Africa
Spain
Switzerland
Turkey
United Kingdom
United States
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 NCT05682378

A Multicenter Study of Continued Current Therapy vs Transition to Ofatumumab After Neurofilament (NfL) Elevation

 		Relapsing-Remitting Multiple Sclerosis Phase4 Canada
United States 		NCT05090371

A Phase III Trial Comparing Tisagenlecleucel to Standard of Care (SoC) in Adult Participants With r/r Follicular Lymphoma

 		Follicular Lymphoma (FL) Phase3 Australia
Canada
Czechia
Hungary
Korea, Republic of
Poland
Romania
Singapore
Slovakia
Spain
Taiwan
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 NCT05888493

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

 		Glioblastoma Phase1 France
Portugal
Spain
Switzerland
United States
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 NCT05109728

Study of 225Ac-PSMA-617 in Men With PSMA-positive Prostate Cancer

 		Prostatic Neoplasms, Castration-Resistant Phase1 Australia
South Africa 		NCT04597411

Study of Out of Specification for Tisagenlecleucel

 		B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma Phase3 Japan NCT04094311

Study of Efficacy and Safety of LCZ696/Amlodipine in Grade 1 and 2 Hypertension Patients Uncontrolled by LCZ696 Monotherapy

 		Hypertension Phase3 Japan NCT06236061

Kesimpta Pregnancy and Infant Safety Study Using Real World Data

 		Multiple Sclerosis Switzerland NCT06156683