Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

Atypical Hemolytic Uremic Syndrome Phase 3 United States
Greece
China
Brazil
Slovakia
Japan
India
Austria
Slovenia
United Kingdom
Czech Republic
Korea, Republic of
Taiwan
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Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

Symptomatic Knee Osteoarthritis Phase 2 United States
Germany
Czech Republic
Romania
Hungary
Argentina
Spain
Slovakia
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STIMULUS MDS-US : Sabatolimab Added to HMA in Higher Risk MDS

Myelodysplastic Syndrome (MDS) Phase 2 United States

Asciminib Roll-over Study

Chronic Myelogenous Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive Phase 4 United States
Spain
Germany
France
Czech Republic
Argentina
Denmark
Portugal
Italy
Mexico
Canada
Russian Federation
United Kingdom
Brazil
Turkey
Romania
Bulgaria
Poland
Austria
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A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors

Mesothelioma Phase 1 United States
Spain
Japan
Germany
United Kingdom
Australia
Italy
Canada
Netherlands
France
Switzerland
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Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

C3G Phase 3 Turkey
Japan
Greece
United States
Spain
Brazil
Switzerland
Argentina
Germany
United Kingdom
France
Canada
India
Israel
Czech Republic
Italy
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Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion Dependence

Myelodysplastic Syndromes Phase 2 Japan

Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS

Multiple Sclerosis Phase 3 France
Spain
Germany
Italy
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Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria Phase 3 United States
Italy
Taiwan
Turkey
Malaysia
United Kingdom
France
Korea, Republic of
Singapore
Germany
Lithuania
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Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.

Glioblastoma Multiforme, Brain Neoplasms, Gastroesophageal Adenocarcinoma, Pancreatic Ductal Adenocarcinoma Early Phase 1 Germany