Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies

Heterozygous or Homozygous Familial Hypercholesterolemia Phase 3 Spain
Netherlands
Lebanon
South Africa
United States
Brazil
Germany
Switzerland
Turkey
Israel
Russian Federation
Slovenia
United Kingdom
Italy
Norway
Hungary
Canada
Taiwan
France
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Long-term Extension Study of Ligelizumab in Food Allergy

Food Allergy Phase 3 United States
France
Spain
Germany
Italy
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24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

Chronic Spontaneous Urticaria Phase 3 United States
Turkey
Thailand
Spain
Italy
China
Germany
Argentina
Netherlands
Hong Kong
Japan
Malaysia
Poland
Canada
Chile
Singapore
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Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy

Macular Polypoidal Choroidal Vasculopathy (PCV) Phase 3 Korea, Republic of

A Study Evaluating [177Lu]Lu-PSMA-617 vs. a Change of Androgen Receptor-directed Therapy in Taxane Treatment Naive Chinese Male Patients With Progressive Metastatic Castrate Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer (mCRPC) Phase 2 China

Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)

Primary Immune Thrombocytopenia (ITP) Phase 3 United States
Turkey
Thailand
Spain
China
United Kingdom
Italy
Czech Republic
Belgium
Romania
Hungary
Argentina
France
Australia
Japan
Mexico
Germany
Norway
Vietnam
Hong Kong
Austria
Malaysia
India
Bulgaria
Singapore
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A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids

Primary Immune Thrombocytopenia Phase 3 United States
Turkey
Japan
Thailand
Spain
China
Italy
Czech Republic
Romania
Hungary
Argentina
India
Australia
Germany
Norway
Korea, Republic of
Malaysia
Taiwan
Belgium
Austria
United Kingdom
Philippines
Singapore
Netherlands
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A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia

Warm Autoimmune Hemolytic Anemia (wAIHA) Phase 3 United States
Israel
Japan
Italy
Thailand
Spain
France
Romania
Argentina
Australia
China
Hungary
Germany
Malaysia
United Kingdom
India
Singapore
Taiwan
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A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis Phase 2 Israel
United Kingdom

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

Systemic Lupus Erythematosus Phase 3 United States
Turkey
Spain
Thailand
China
Brazil
Portugal
Slovakia
Czech Republic
Poland
South Africa
Japan
Guatemala
Hungary
Israel
Bulgaria
Canada
Singapore
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