Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers Phase1 Belgium
China
France
Germany
Israel
Italy
Japan
Korea, Republic of
Norway
Singapore
Spain
Sweden
Taiwan
United Kingdom
United States
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Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

Systemic Lupus Erythematosus Phase3 Argentina
Australia
Bulgaria
Canada
China
Czechia
France
Germany
Guatemala
Hungary
Japan
Malaysia
Poland
Portugal
Romania
Spain
Taiwan
Thailand
United States
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Asciminib Prospective Non Interventional Study as 3rd Line Therapy or More to Treat Adult Patients With CML- CP in Real World Setting in France

Chronic Myeloid Leukemia France

[177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer

Breast Cancer Phase1 China
France
Germany
Poland
Portugal
Spain
United States
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Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL

Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Diffuse Large B-cell Lymphoma, Acute Lymphoblastic Leukemia, Large B-cell Lymphoma Phase1, Phase2 Australia
Austria
France
Germany
Italy
Japan
Spain
United States
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Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Atypical Hemolytic Uremic Syndrome Phase3 Brazil
China
Czechia
India
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Kesimpta (Ofatumumab) Pregnancy Registry

Multiple Sclerosis, Pregnancy United States

Effectiveness and Safety of Dabrafenib in Combination With Trametinib as Adjuvant Treatment for Chinese Patients With Stage III BRAF V600 Mutation-positive Melanoma After Complete Resection

Melanoma China

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

Metastatic Uveal Melanoma Phase1, Phase2 Australia
France
Germany
Netherlands
Spain
Switzerland
United States
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A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors

Mesothelioma Phase1 Australia
Canada
France
Germany
Italy
Japan
Netherlands
Spain
Switzerland
United Kingdom
United States
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