Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

Progressive Metastatic Castrate Resistant Prostate Cancer Phase1, Phase2 Australia
China
Denmark
France
Italy
Malaysia
Poland
Singapore
Spain
United States
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Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

Graft vs. Host Disease, Chronic Graft vs. Host Disease, Corticosteroid-refractory Chronic Graft vs. Host Disease Phase4 China

RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia

HR+/HER2- Early Breast Cancer Saudi Arabia

NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice

Paroxysmal Nocturnal Hemoglobinuria Russia

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Relapsing Multiple Sclerosis Phase3 Argentina
Australia
Belgium
Canada
Denmark
France
Greece
Italy
Mexico
Portugal
Slovakia
South Africa
Spain
Switzerland
United Kingdom
United States
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Pelacarsen Roll-over Extension Program

Atherosclerotic Cardiovascular Disease Phase3 Puerto Rico
United States

Long-term Follow up Local Registry Study of Kymriah in South Korea

B-Cell Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma South Korea

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

Kidney Diseases, Kidney Diseases, Chronic, Urological Diseases, Glomerulonephritis, Glomerular Disease, Glomerulonephritis, IGA, Glomerulopathy, Immunoglobulin Disease Phase3 Argentina
South Korea
United States

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Prostate Cancer Phase3 Australia
Brazil
China
Hong Kong
India
Japan
Singapore
South Korea
Taiwan
United Kingdom
United States
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Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

Glomerulonephritis, IGA, Immunoglobulin A Nephropathy Phase2 Argentina
Israel
Malaysia
United States
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