Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis

Moderate-to-severe Plaque Psoriasis Russian Federation

Study to Assess the Efficacy and Safety of Alpelisib Plus Fulvestrant in Participants With HR-postitive (HR+), HER2-negative, Advanced Breast Cancer After Treatment With a CDK4/6 Inhibitor and an Aromatase Inhibitor.

Breast Cancer Phase3 Spain
Denmark
Greece
Germany
Italy
France
Slovakia
Czechia
Belgium
Hungary
Poland
Canada
Portugal
Romania
Ireland
Finland
Bulgaria
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A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

Coronary Heart Disease, Clonal Hematopoiesis of Indeterminate Potential (CHIP) Phase2 Germany
Canada
United States

Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

Symptomatic Knee Osteoarthritis Phase2 United States
Germany
Czechia
Romania
Hungary
Argentina
Spain
Slovakia
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To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria

Severe Malaria Phase2 Côte D'Ivoire
Burkina Faso
Nigeria
Rwanda
Congo, The Democratic Republic of the
Gabon
India
Kenya
Uganda
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Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

Relapsing Multiple Sclerosis Phase3 United States
United Arab Emirates
Spain
Jordan
Belgium
Israel
Lebanon
China
Switzerland
Colombia
Slovakia
Argentina
Poland
India
Ireland
Austria
Guatemala
Saudi Arabia
Taiwan
Lithuania
Malaysia
Italy
Croatia
Bulgaria
Latvia
Netherlands
Chile
Hong Kong
Denmark
Georgia
United Kingdom
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Survey Among Healthcare Professionals Treating Patients With Metastatic Breast Cancer in Selected European Countries to Evaluate Their Knowledge on Management of Hyperglycemia When Using Alpelisib

Breast Cancer Switzerland

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic Phase2 United States
Greece
Spain
Italy
Turkey
Malaysia
Czechia
China
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A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

Primary IgA Nephropathy Phase3 United States
Denmark
Australia
Israel
India
Thailand
China
Norway
Germany
Korea, Republic of
Argentina
Brazil
Belgium
Netherlands
Hong Kong
Turkey
Taiwan
Malaysia
Japan
United Kingdom
Italy
Canada
France
Czechia
Singapore
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Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera

Polycythemia Vera Italy