Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

 		Familial Hypercholesterolemia - Heterozygous Phase3 Argentina
Austria
China
Czechia
France
Germany
Hungary
Israel
Italy
Malaysia
Poland
Portugal
Spain
United States
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 NCT06597019

A Prospective Non-interventional Study to Evaluate Clinical Outcomes of Ribociclib Combined With Endocrine Therapy in Elderly Patients With HR+HER2 - Advanced Breast Cancer in Routine Clinical Practice in Russian Federation

 		HR+HER2- Advanced Breast Cancer Russian Federation NCT06625333

An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB323 in Relapsing Multiple Sclerosis

 		Relapsing Multiple Sclerosis Phase1, Phase2 Australia
Switzerland 		NCT06617793

ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS

 		Relapsing Remitting Multiple Sclerosis (RRMS) Phase4 Canada NCT06733922

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

 		Metastatic Castration-Resistant Prostate Cancer Phase1 Netherlands
Spain
United Kingdom
United States
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 NCT06531499

Phase 2 Study of Rapcabtagene Autoleucel in Myositis

 		Idiopathic Inflammatory Myopathies Phase2 France
Germany
Israel
Italy
Japan
Singapore
Taiwan
United States
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 NCT06665256

Specified Drug-use Surveillance of Fabhalta Capsules

 		Paroxysmal Nocturnal Hemoglobinuria Japan NCT06606314

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

 		Healthy Volunteers, Pulmonary Arterial Hypertension Phase1, Phase2 United States NCT06649110

An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE).

 		Systemic Lupus Erythematosus, SLE Phase1 Bulgaria
Germany
Netherlands
Spain
Switzerland
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 NCT06335979

A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

 		Sickle Cell Disease Phase3 Colombia
United States 		NCT06439082